Products for Translation in Cells

mRNA Production


T7 mScript™ Standard mRNA Production System
002
Simply the best way to make in vitro mRNA. Combines the benefits of high-yield transcription with those of post-transcriptional capping and tailing all in one kit. See T7-FlashScribe Transcription Kit, ScriptCap m7G Capping System, ScriptCap 2'-O-Methyltransferase Kit and A-Plus Poly(A) Polymerase Tailing Kit on this page.
C-MSC11610     10 reactions     $314
C-MSC100625   25 reactions     $688

In Vitro Transcription


T7-FlashScribe™ Transcription Kit
002
For the production of in vitro transcribed RNA with T7 RNA polymerase and canonical (GAUC) NTPs. A reaction produces 180 µg RNA from 1 µg DNA in
30 minutes.
C-ASF3507        50 reactions     $281

T7-Scribe™ Standard RNA IVT Kit
002
For the production of in vitro transcribed RNA with T7 RNA polymerase and canonical (GAUC) NTPs. A reaction produces 150 µg RNA from 1 µg DNA in 2 hours.
C-AS3107          50 reactions     $262

SP6-Scribe™ Standard RNA IVT Kit
002
For the production of in vitro transcribed RNA with SP6 RNA polymerase and canonical (GAUC) NTPs. A reaction produces 90 µg RNA from 1 µg DNA in 2 hours.
C-AS3106          50 reactions     $262

Post-Transcriptional Capping


ScriptCap™ m7G Capping System
002
For post-transcriptional capping of in vitro transcribed RNA with ScriptCap Capping Enzyme, GTP and SAM. Cap 0 (N7-methyl-G) caps can be built with efficiencies approaching 100%. This cannot be accomplished with co-transcriptional capping methods. Use in conjunction with ScriptCap 2'-O-Methyltransferase to produce
Cap 1 caps, that which is found on most eukaryotic mRNAs.
C-SCCE0625      25 reactions    $427

ScriptCap™ 2'-O-Methyltransferase Kit
002
For conversion of RNA containing Cap 0 caps to those containing Cap 1 caps, which are found on most eukaryotic mRNAs. Can be used simultaneously with ScriptCap m7G Capping System to produce virtually 100% Cap 1-capped RNA in a single reaction.
C-SCMT0625      25 reactions    $215

ScriptCap™ Cap 1 Capping System
002
For post-transcriptional capping of in vitro transcribed RNA with ScriptCap Capping Enzyme, ScriptCap 2'-O-Methyltransferase, GTP and SAM. Either Cap 0 or Cap 1 caps can be built with efficiencies approaching 100%. This cannot be accomplished with co-transcriptional capping methods.
C-SCCS1710      10 reactions    $207

Co-Transcriptional Capping


MessageMAX™ T7 ARCA-Capped Message Transcription Kit
002
For co-transcriptional capping of IVT RNA with T7 RNA polymerase and Anti-Reverse cap analog (ARCA). A reaction produces 60 µg RNA from 1 µg DNA in 30 minutes. Reaction products are 80% correctly capped and 20% uncapped.
C-MMA60710    10 reactions    $317

AmpliCap-Max™ T7 High Yield Message Maker Kit
002
For co-transcriptional capping of IVT RNA with T7 RNA polymerase and standard cap analog. A reaction produces 60 µg RNA from 1 µg DNA in 30 minutes. Reaction products are 40% correctly capped, 40% incorrectly capped and 20% uncapped.
C-ACM04037    25 reactions    $361

AmpliCap™ SP6 High Yield Message Maker Kit
002
For co-transcriptional capping of IVT RNA with SP6 RNA polymerase and standard cap analog. A reaction produces 35 µg RNA from 1 µg DNA in 2 hours. Reaction products are 40% correctly capped, 40% incorrectly capped and 20% uncapped.
C-AC0706         25 reactions    $361

Post-Transcriptional Tailing


A-Plus™ Poly(A) Polymerase Tailing Kit
002
For post-transcriptional poly(A) tail addition to RNAs. Allows tailing of mRNAs
in vitro, to lengths equivalent to or greater than those found in nature. This cannot be accomplished with co-transcriptional tailing methods.
C-PAP5104H     50 reactions    $215

Modified NTP In Vitro Transcription


INCOGNITO™ T7 Ψ-RNA Transcription Kit
002
For the production of pseudouridine-containing, in vitro transcribed RNA with T7 RNA polymerase. Ψ-mRNAs induce lower innate immune responses in mammalian cells. A reaction produces 100 µg RNA from 1 µg DNA in 2 hours.
C-ICTY110510  10 reactions    $402

INCOGNITO™ SP6 Ψ-RNA Transcription Kit
002
For the production of pseudouridine-containing, in vitro transcribed RNA with SP6 RNA polymerase. Ψ-mRNAs induce lower innate immune responses in mammalian cells. A reaction produces 60 µg RNA from 1 µg DNA in 2 hours.
C-ICSY110510  10 reactions    $402

INCOGNITO™ T7 5mC- & Ψ-RNA Transcription Kit
002
For the production of 5-methylcytosine- pseudouridine-containing, in vitro transcribed RNA with T7 RNA polymerase. 5mC- Ψ-mRNAs induce lower innate immune responses in mammalian cells. A reaction produces 100 µg RNA from 1 µg DNA in 2 hours.
C-ICTMY110510   10 reactions   $677

INCOGNITO™ T7 ARCA 5mC- & Ψ-RNA Transcription Kit
002
For co-transcriptional capping of 5-methylcytosine- pseudouridine-containing,
in vitro transcribed RNA with T7 RNA polymerase and Anti-Reverse cap analog (ARCA). 5mC- Ψ-mRNAs induce lower innate immune responses in mammalian cells. A reaction produces 40 µg RNA from 1 µg DNA in 3 hours. Reaction products are 80% correctly capped and 20% uncapped.
C-ICTAMY110510  10 reactions  $825

mRNA Decapping


Cap-Clip™ Acid Pyrophosphatase
002
For the removal of cap structures (decapping) from various RNAs (i.e. mRNAs) resulting in 5'-monophosphate RNAs. Can be substituted unit for unit, into any preexisting protocol for Tobacco Acid Pyrophosphatase (TAP) utilizing the same buffer.
C-CC15011H   100 units       $550

RNase Inhibition


ScriptGuard™ RNase Inhibitor
002
Inhibits eukaryotic RNases A, B and C. Use as a safeguard against RNA degradation in any RNA-containing reaction.
C-SRI6310K    10,000 units   $273

Recently Discontinued

The Products listed below have recently been discontinued. We will continue to sell until inventory is depleted. Please inquire for current stock levels. Thank you for your understanding.

Product Size Product # Price Literature
Anti-Reverse Cap Analog (ARCA) 500 nmol C-C50110 $128.00 002
PseudoU-RNA Molecular Weight Markers 25 lanes C-PRM101125 $250.00  002
ScriptCap™ 2'-O-Methyltransferase Kit 10 rxns C-SCMT0610 $78.00 002
ScriptCap™ m7G Capping System 10 rxns C-SCCE0610 $188.00  002
ScriptGuard™ RNase Inhibitor 2,500 units C-SRI6325 $98.00  002
T7-Scribe™ Standard RNA IVT Kit 25 rxns C-AS2607 $155.00 002

The Products listed above are currently offered by CELLSCRIPT™ for research use only under the defined Terms and Conditions. To place an order, visit How To Order.

Contact CELLSCRIPT™ to inquire about customizations of existing products or manufacturing of products for other uses, such as therapeutics, which may require meeting regulatory standards, such as use of components that are not derived from animal origin.